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Activation of the cAMP transduction cascade contributes to the mechanical hyperalgesia and allodynia induced by intradermal injection of capsaicin
1. The spinal role of the cAMP transduction cascade in nociceptive processing was investigated in awake behaving rats (male, Sprague-Dawley) by activating or inhibiting this pathway spinally. Microdialysis fibres were implanted into the dorsal horn to infuse drugs directly to the spinal cord. 2. Ani...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
1997
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1565045/ https://ncbi.nlm.nih.gov/pubmed/9401782 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701486 |
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