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Effect of pentoxifylline on the degradation of procollagen type I produced by human hepatic stellate cells in response to transforming growth factor-β(1)

1. Pentoxifylline (PTF) may act as a potential antifibrogenic agent by inhibiting cell proliferation and/or collagen deposition in cell type(s) responsible for the accumulation of extracellular matrix. The aim of the present study was to investigate at which level PTF may affect synthesis and degrad...

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Bibliografiska uppgifter
Huvudupphovsmän: Giulio Romanelli, Roberto, Caligiuri, Alessandra, Carloni, Vinicio, DeFranco, Raffaella, Montalto, Paolo, Ceni, Elisabetta, Casini, Alessandro, Gentilini, Paolo, Pinzani, Massimo
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1997
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565043/
https://ncbi.nlm.nih.gov/pubmed/9401768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701484
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