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Differential regulation of cyclo-oxygenase-2 and 5-lipoxygenase-activating protein (FLAP) expression by glucocorticoids in monocytic cells

1. The objective of the present study was to determine the effects of dexamethasone on key constituents of prostaglandin and leukotriene biosynthesis, cyclo-oxygenase-2 (COX-2) and 5-lipoxygenase activating protein (FLAP). The human monocytic cell line THP-1 was used as a model system. mRNA and prot...

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Hlavní autoři: Goppelt-Struebe, M, Schaefer, D, Habenicht, A J R
Médium: Artigo
Jazyk:Inglês
Vydáno: 1997
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1564983/
https://ncbi.nlm.nih.gov/pubmed/9375956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701425
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