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Effects of ibuprofen enantiomers and its coenzyme A thioesters on human prostaglandin endoperoxide synthases

1. Ibuprofen enantiomers and their respective coenzyme A thioesters were tested in human platelets and blood monocytes to determine their selectivity and potency as inhibitors of cyclo-oxygenase activity of prostaglandin endoperoxide synthase-1 (PGHS-1) and PGHS-2. 2. Human blood from volunteers was...

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Autori principali: Neupert, Werner, Brugger, Roland, Euchenhofer, Christian, Brune, Kay, Geisslinger, Gerd
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1997
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1564971/
https://ncbi.nlm.nih.gov/pubmed/9351505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701415
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