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In vitro and in vivo characterization of NK(3) receptors in the rabbit eye by use of selective non-peptide NK(3) receptor antagonists

1. Inhibition of NK(3) receptor agonist-induced contraction in the rabbit isolated iris sphincter muscle was used to assess the in vitro functional activity of three 2-phenyl-4-quinolinecarboxamides, members of a novel class of potent and selective non-peptide NK(3) receptor antagonists. In addition...

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Detalhes bibliográficos
Main Authors: Medhurst, Andrew D, Hay, Douglas W P, Parsons, Andrew A, Martin, Lenox D, Griswold, Don E
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1564965/
https://ncbi.nlm.nih.gov/pubmed/9351503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701406
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