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Inhibitory effects of (±)-propranolol on excitation-contraction coupling in isolated soleus muscles of the rat

1. The effect of a β-adrenoceptor antagonist, propranolol, was investigated on excitation-contraction coupling in small, intact bundles of soleus muscle fibres from the rat. 2. (±)-Propranolol significantly inhibited twitch and tetanic tension with IC(50) values of 6.7 μM and 3.5 μM, respectively. 3...

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Detalhes bibliográficos
Main Authors: Ha, Tuyen N V, Fryer, Martin W
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1564964/
https://ncbi.nlm.nih.gov/pubmed/9351502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701405
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