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Potent and voltage-dependent block by philanthotoxin-343 of neuronal nicotinic receptor/channels in PC12 cells

1. Block by philanthotoxin-343 (PhTX-343), a neurotoxin from wasps, of ionic currents mediated through neuronal nicotinic acetylcholine (ACh) receptor/channels was characterized in rat phaeochromocytoma PC12 cells, by use of whole cell voltage-clamp techniques. 2. In the cells held at −60 mV, PhTX-3...

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Detalhes bibliográficos
Main Authors: Liu, Min, Nakazawa, Ken, Inou, Kazuhide, Ohno, Yasuo
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1564930/
https://ncbi.nlm.nih.gov/pubmed/9313950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701373
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