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The antiarrhythmic agent bertosamil induces inactivation of the sustained outward K(+) current in human atrial myocytes
1. In whole-cell patch-clamped human atrial myocytes, the antiarrhythmic agent bertosamil (10 μM) inhibited the sustained component, I(sus) (38.6±3.1%), and enhanced the inactivating component, I(t) (9.1±6.1%), of the outward K(+) current elicited by 750 ms test pulses from −60 mV to +50 mV. Higher...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
1997
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1564926/ https://ncbi.nlm.nih.gov/pubmed/9313938 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701369 |
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