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Cardiac effects of quinidine on guinea-pig isolated perfused hearts after in vivo quinidine pretreatment
1. Experimental and clinical studies suggest that class I and class III antiarrhythmic drugs may be subject to pharmacological tolerance during long term treatment, leading to loss of therapeutic effectiveness. 2. The aim of this study was to ascertain whether prolonged in vivo treatment with the Cl...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1997
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1564892/ https://ncbi.nlm.nih.gov/pubmed/9298522 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701318 |
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