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Evidence for the involvement of P(2)-purinoceptors in the cholinergic contraction of the guinea-pig ileum

In the isolated ileum of the guinea-pig the P(2)-purinoceptor antagonists PPADS and suramin: (a) strongly inhibited the cholinergic contractile effect of α,β-methylene ATP, (b) did not influence contractions evoked by exogenous acetylcholine (ACh) but, (c) moderately (by about 30%) inhibited choline...

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Autors principals: Barthó, Loránd, Lénárd, László, Maggi, Carlo A
Format: Artigo
Idioma:Inglês
Publicat: 1997
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1564888/
https://ncbi.nlm.nih.gov/pubmed/9283681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701350
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