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Activation of microsomal cytochrome P450 mono-oxygenase by Ca(2+) store depletion and its contribution to Ca(2+) entry in porcine aortic endothelial cells

1. We investigated how microsomal cytochrome P450 mono-oxygenase (Cyp450 MO) is regulated in cultured porcine aortic endothelial cells. The hypothesis that a Cyp450 MO-derived metabolite links Ca(2+) store depletion and Ca(2+) entry was studied further. 2. Microsomal Cyp450 MO was monitored fluorome...

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Detalhes bibliográficos
Main Authors: Hoebel, Bernhard G, Kostner, Gert M, Graier, Wolfgang F
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1564862/
https://ncbi.nlm.nih.gov/pubmed/9283690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701304
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