The spasmogenic effects of vanadate in human isolated bronchus

1. Inhalation of vanadium compounds, particularly vanadate, is a cause of occupational bronchial asthma. We have now studied the action of vanadate on human isolated bronchus. Vanadate (0.1 μM–3 mM) produced concentration-dependent, well-sustained contraction. Its −logEC(50) was 3.74±0.05 (mean±s.e....

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Bibliografische gegevens
Hoofdauteurs: Cortijo, Julio, Villagrasa, Victoria, Martí-Cabrera, Miguel, Villar, Vicente, Moreau, Joelle, Advenier, Charles, Morcillo, Esteban J, Small, Roger C
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1997
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Papers
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1564836/
https://ncbi.nlm.nih.gov/pubmed/9257912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701277
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