Pharmacological evaluation of IQM-95,333, a highly selective CCK(A) receptor antagonist with anxiolytic-like activity in animal models

1. The pyridopyrimidine derivative IQM-95,333 ((4aS,5R)-2-benzyl-5-[N(α)-tert-butoxicarbonyl)L-tryptophyl]amino-1,3dioxoperhydropyrido[1,2-c]pyrimidine), a new non-peptide antagonist of cholecystokinin type A (CCK(A)) receptors, has been evaluated in vitro and in vivo in comparison with typical CCK(...

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Main Authors: Ballaz, Santiago, Barber, Ana, Fortuño, Ana, Del Río, Joaquín, Martín-Martínez, Mercedes, Gómez-Monterrey, Isabel, Herranz, Rosario, González-Muñiz, Rosario, García-López, Maria-Teresa
Format: Artigo
Language:Inglês
Published: 1997
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Papers
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1564744/
https://ncbi.nlm.nih.gov/pubmed/9208145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701186
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