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Inhibition of Ca(2+) channel current by μ- and κ-opioid receptors coexpressed in Xenopus oocytes: desensitization dependence on Ca(2+) channel α(1) subunits

1. Desensitization of μ- and κ-opioid receptor-mediated inhibition of voltage-dependent Ca(2+) channels was studied in a Xenopus oocyte translation system. 2. In the oocytes coexpressing κ-opioid receptors with N- or Q-type Ca(2+) channel α(1) and β subunits, the κ-agonist, U50488H, inhibited both n...

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Main Authors: Kaneko, Shuji, Yada, Nobumichi, Fukuda, Koichiro, Kikuwaka, Masanobu, Akaike, Akinori, Satoh, Masamichi
Formáid: Artigo
Teanga:Inglês
Foilsithe: 1997
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1564739/
https://ncbi.nlm.nih.gov/pubmed/9208152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701181
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