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Interactions between imidazoline compounds and sulphonylureas in the regulation of insulin secretion

1. Imidazoline α(2)-antagonist drugs such as efaroxan have been shown to increase the insulin secretory response to sulphonylureas from rat pancreatic B-cells. We have investigated whether this reflects binding to an islet imidazoline receptor or whether α(2)-adrenoceptor antagonism is involved. 2....

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Detalhes bibliográficos
Main Authors: Mourtada, Mirna, Brown, Colin A, Smith, Stephen A, Piercy, Valerie, Chan, Susan L F, Morgan, Noel G
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1564733/
https://ncbi.nlm.nih.gov/pubmed/9208151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701172
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