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Characterization of the vasodilator properties of peroxynitrite on rat pulmonary artery: role of poly (adenosine 5′-diphosphoribose) synthase

1. The pulmonary vasculature is constantly exposed to oxygen and reactive oxygen species such as nitric oxide (NO) and superoxide anions which can combine at a near diffusion limited rate, to form the powerful oxidant, peroxynitrite (ONOO(−)). When formed in large amounts, ONOO(−) is thought to cont...

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Autors principals: Chabot, Francois, Mitchell, Jane A, Quinlan, Gregory J, Evans, Timothy W
Format: Artigo
Idioma:Inglês
Publicat: 1997
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1564715/
https://ncbi.nlm.nih.gov/pubmed/9179390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701162
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