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The in vitro pulmonary vascular effects of FK409 (nitric oxide donor): a study in normotensive and pulmonary hypertensive rats

1. Vasorelaxant responses to the nitric oxide (NO) donor, FK409 ((±)-(E)-4-ethyl-2-[(E)-hydroxyimino]-5-nitro-3-hexenamide), were evaluated on precontracted isolated ring preparations of main pulmonary artery and intralobar pulmonary artery from rats. 2. On main pulmonary artery FK409 fully reversed...

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Detalhes bibliográficos
Main Authors: Wanstall, Janet C, Kaye, Jacqueline A, Gambino, Agatha
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1564669/
https://ncbi.nlm.nih.gov/pubmed/9154338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701105
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