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Down-regulation of aortic and cardiac AT(1) receptor gene expression in transgenic (mRen-2) 27 rats

1. Transgenic(TG) (mRen-2) rats overexpressing the mouse renin gene develop fulminant hypertension and cardiac hypertrophy. Since the activation of AT(1) receptor by angiotensin II is involved in blood pressure regulation, cardiac performance and myocardial growth, we investigated the biological eff...

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Detalhes bibliográficos
Main Authors: Nickenig, G, Laufs, U, Schnabel, P, Knorr, A, Paul, M, Böhm, M
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1564644/
https://ncbi.nlm.nih.gov/pubmed/9146897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701088
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