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Investigation of role for oxidant stress in vascular tolerance development to glyceryl trinitrate in vitro

1. The role of reactive oxygen species (ROS) during the development of vascular cellular tolerance to glyceryl trinitrate (GTN), was studied in the rat isolated aorta. 2. Nitrate tolerance induced by a 30 min incubation with GTN (30 or 100 μM) in vitro, was not affected by pretreatment with the intr...

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Autors principals: Laight, David W, Carrier, Martin J, Änggård, Erik E
Format: Artigo
Idioma:Inglês
Publicat: 1997
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1564632/
https://ncbi.nlm.nih.gov/pubmed/9113368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701078
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