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The effect of ketotifen on nitric oxide synthase activity

1. We studied the effect of ketotifen, a second generation H(1)-receptor antagonist on nitric oxide synthase (NOS) activity in colonic mucosa and in renal tissues, and on rat renal haemodynamics in vivo. 2. Ketotifen (100 μg ml(−1)) increased human colonic NOS activity from 3.7±0.6 to 14.5±1.3 nmol ...

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Main Authors: Heyman, Samuel N, Karmeli, Fanny, Brezis, Mayer, Rachmilewitz, Daniel
Format: Artigo
Jezik:Inglês
Izdano: 1997
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1564622/
https://ncbi.nlm.nih.gov/pubmed/9113377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701063
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