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Sites of action of IL-1 in the development of fever and cytokine responses to tissue inflammation in the rat

1. The objective of the present study was to determine the sites of action of the cytokine, interleukin-1 (IL-1), in the febrile response to local inflammation in the rat, by comparing the importance of IL-1 in the local tissues, the circulation and the brain. This was achieved by injecting lipopoly...

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Detalhes bibliográficos
Main Authors: Miller, Andrew J, Hopkins, Stephen J, Luheshi, Giamal N
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1564605/
https://ncbi.nlm.nih.gov/pubmed/9105702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701049
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