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An autoradiographic study of dextromethorphan high-affinity binding sites in rat brain: sodium-dependency and colocalization with paroxetine

1. The distribution and some pharmacological properties of centrally located dextromethorphan high-affinity binding sites were investigated by in vitro autoradiography. 2. Sodium chloride (50 mM) induced a 7 to 12 fold increase in dextromethorphan binding to rat brain in all areas tested. The effect...

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Detalhes bibliográficos
Main Authors: Meoni, P, Tortella, F C, Bowery, N G
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1564602/
https://ncbi.nlm.nih.gov/pubmed/9105700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701043
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