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Effect of short-term and long-term treatments with σ ligands on the N-methyl-D-aspartate response in the CA(3) region of the rat dorsal hippocampus

1. Long-term treatments with the σ ligand haloperidol decrease the density of σ receptors in mammalian CNS. We have shown that σ ligands, such as di(2-tolyl)guanidin (DTG), potentiate dose-dependently, with bell-shaped dose-response curves, the neuronal response of pyramidal neurones to N-methyl-D-a...

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Detalhes bibliográficos
Main Authors: Bergeron, Richard, de Montigny, Claude, Debonnel, Guy
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1564601/
https://ncbi.nlm.nih.gov/pubmed/9105712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701042
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