Induction of cyclo-oxygenase-2 by cytokines in human cultured airway smooth muscle cells: novel inflammatory role of this cell type

1. Cyclo-oxygenase (COX) is the enzyme that converts arachidonic acid to prostaglandin H(2) (PGH(2)) which can then be further metabolized to prostanoids which modulate various airway functions. COX exists in at least two isoforms. COX-1 is expressed constitutively, whereas COX-2 is expressed in res...

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Autores principales: Belvisi, Maria G, Saunders, Michael A, Haddad, El-Bdaoui, Hirst, Stuart J, Yacoub, Magdi H, Barnes, Peter J, Mitchell, Jane A
Formato: Artigo
Lenguaje:Inglês
Publicado: 1997
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Papers
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1564529/
https://ncbi.nlm.nih.gov/pubmed/9138698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0700963
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