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Inhibition of delayed rectifier K(+) channels by phenytoin in rat neuroblastoma cells

1. The action of the anticonvulsant drug phenytoin on K(+) currents was investigated in neuroblastoma cells by whole-cell voltage-clamp recording. 2. Neuroblastoma cells expressed an outward K(+) current with a voltage- and time-dependence which resembled the delayed-rectifier K(+) current found in...

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Hlavní autoři: Nobile, Mario, Vercellino, Paolo
Médium: Artigo
Jazyk:Inglês
Vydáno: 1997
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1564518/
https://ncbi.nlm.nih.gov/pubmed/9051303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0700969
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