Evidence against a role of cytochrome P450-derived arachidonic acid metabolites in endothelium-dependent hyperpolarization by acetylcholine in rat isolated mesenteric artery

1. In rat mesenteric artery, acetylcholine (ACh) causes endothelium-dependent hyperpolarization by releasing endothelium-derived hyerpolarizing factor (EDHF). Recent evidence suggests that EDHF may be a cytochrome P450-derived arachidonic acid metabolite. The aim of the present study was to investig...

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Bibliografiske detaljer
Main Authors: Fukao, Mitsuhiro, Hattori, Yuichi, Kanno, Morio, Sakuma, Ichiro, Kitabatake, Akira
Format: Artigo
Sprog:Inglês
Udgivet: 1997
Fag:
Papers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1564487/
https://ncbi.nlm.nih.gov/pubmed/9031747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0700932
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