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Low dose aerosol infection of mice with virulent type A Francisella tularensis induces severe thymus atrophy and CD4(+) CD8(+) thymocyte depletion
Francisella tularensis is a gram-negative facultative intracellular bacterium and the causative agent of tularemia. Two subspecies (type A and B strains) of the pathogen exist, the former being much more virulent than the latter for humans and other higher mammals. In this study, we examined the eff...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1564440/ https://ncbi.nlm.nih.gov/pubmed/16257504 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.micpath.2005.08.005 |
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