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The evaluation of the factors that cause aggregation during recombinant expression in E. coli is simplified by the employment of an aggregation-sensitive reporter

BACKGROUND: The yields of soluble recombinant proteins expressed in bacteria are often low due to the tendency of the heterologous proteins to form aggregates. Therefore, aggregation reporters have been envisaged to simplify the comparison among different expression conditions and to speed up the id...

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Detalhes bibliográficos
Principais autores: Schultz, Tina, Martinez, Lucia, de Marco, Ario
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1564408/
https://ncbi.nlm.nih.gov/pubmed/16948849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2859-5-28
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