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Activation of ecto-5′-nucleotidase by protein kinase C and its role in ischaemic tolerance in the canine heart

1. Ischaemic preconditioning (IP) protects the myocardium against irreversible ischaemic injury by activating protein kinase C (PKC). The mechanism by which PKC protects the myocardium is unknown. We have shown that PKC increases the activity of ecto-5′-nucleotidase (ecto-5′-N) and thereby the produ...

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Detalhes bibliográficos
Main Authors: Node, Koichi, Kitakaze, Masafumi, Minamino, Tetsuo, Tada, Michihiko, Inoue, Michitoshi, Hori, Masatsugu, Kamada, Takenobu
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1564367/
https://ncbi.nlm.nih.gov/pubmed/9117120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0700890
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