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Dose- and time-dependence of L-NAME neuroprotection in transient focal cerebral ischaemia in rats
1. In this study the effect of the dose and administration time of N(G)-nitro-L-arginine methyl ester (L-NAME), an NO-synthase inhibitor, in a model of transient focal cerebral ischaemia in rats was investigated. 2. Two injections of L-NAME were given, of 1, 3 and 10 mg kg(−1), 5 min and 3 h after t...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
1996
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1564357/ https://ncbi.nlm.nih.gov/pubmed/9117092 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0700889 |
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