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Antagonist inhibition curves and the measurement of dissociation constants

1. Experiments carried out on guinea-pig isolated ileum with carbachol as agonist and diphenyl- acetoxyethyl- dimethyl-ethyl- ammonium (DADMEA) bromide as antagonist gave results which fit the theoretical relation between fractional inhibition (Q) of the effects of an agonist ([A]) and the concentra...

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Библиографические подробности
Главные авторы: Barlow, R B, Bond, Susan M, Bream, Elizabeth, Macfarlane, Lisa, McQueen, D S
Формат: Artigo
Язык:Inglês
Опубликовано: 1996
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1564343/
https://ncbi.nlm.nih.gov/pubmed/9117087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0700865
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