In vivo and in vitro evidence of altered nitric oxide metabolism in the spontaneously diabetic, insulin-dependent BB/Edinburgh rat

1. Altered vasoreactivity may contribute significantly to the pathogenesis of diabetic vascular complications. This study investigated the effect of (a) insulin-treated diabetes, and (b) chronic in vivo administration of N(ω)-nitro-L-arginine methyl ester (L-NAME), a nitric oxide (NO) synthase inhib...

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Autors principals: Lindsey, R Mark, Peet, Rosemary S, Wilkie, Gavin S, Rossiter, Sharon P, Smith, William, Baird, Joyce D, Williams, Brent C
Format: Artigo
Idioma:Inglês
Publicat: 1996
Matèries:
Papers
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1564340/
https://ncbi.nlm.nih.gov/pubmed/9117082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0700862
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