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Hmgb3 regulates the balance between hematopoietic stem cell self-renewal and differentiation
Hmgb3 is an X-linked member of a family of sequence-independent chromatin-binding proteins that is preferentially expressed in hematopoietic stem cells (HSC). Hmgb3-deficient mice (Hmgb3(−/Y)) contain normal numbers of HSCs, capable of self-renewal and hematopoietic repopulation, but fewer common ly...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1564268/ https://ncbi.nlm.nih.gov/pubmed/16945912 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0604006103 |
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