Suppression of Tumor Recurrence and Metastasis by a Combination of the PHSCN Sequence and the Antiangiogenic Compound Tetrathiomolybdate in Prostate Carcinoma

Plasma fibronectin-mediated invasion of human DU145 prostate cancer cell line was efficaciously inhibited in a rat tumor model by treatment with Ac-PHSCN-NH(2) peptide. Invasion of DU145 cells was stimulated by the PHSRN sequence of plasma fibronectin. However, PHSCN acts as a competitive inhibitor...

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Hlavní autoři: van Golen, Kenneth L, Bao, LiWei, Brewer, George J, Pienta, Kenneth J, Kamradt, Jeffrey M, Livant, Donna L, Merajver, Sofia D
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2002
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Brief Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1564117/
https://ncbi.nlm.nih.gov/pubmed/12192595
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