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Adiponectin-induced secretion of interleukin-6 (IL-6), monocyte chemotactic protein-1 (MCP-1, CCL2) and interleukin-8 (IL-8, CXCL8) is impaired in monocytes from patients with type I diabetes

BACKGROUND: Systemic adiponectin is reduced in patients with cardiovascular disease (CVD) and low adiponectin may contribute to the pathogenesis of atherosclerosis. However, circulating adiponectin is elevated in type 1 diabetes (T1D) patients, who have also a higher incidence to develop CVD. Becaus...

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Detalhes bibliográficos
Main Authors: Abke, Sabine, Neumeier, Markus, Weigert, Johanna, Wehrwein, Gabriele, Eggenhofer, Elke, Schäffler, Andreas, Maier, Kevin, Aslanidis, Charalampos, Schölmerich, Jürgen, Buechler, Christa
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1563998/
https://ncbi.nlm.nih.gov/pubmed/16939660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2840-5-17
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