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Low dose endotoxin priming is accountable for coagulation abnormalities and organ damage observed in the Shwartzman reaction. A comparison between a single-dose endotoxemia model and a double-hit endotoxin-induced Shwartzman reaction

The clinical response of sepsis to a systemic inflammatory infection may be complicated by disseminated intravascular coagulation or DIC. In order to experimentally study the syndrome of DIC, we aimed for a severe sepsis model complicated by disseminated coagulation. Most -simplified- experimental m...

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Bibliografiske detaljer
Main Authors: Slofstra, Sjoukje H, Cate, Hugo ten, Spek, C Arnold
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1563996/
https://ncbi.nlm.nih.gov/pubmed/16930474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-9560-4-13
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