Tertiary Structural and Functional Analyses of a Viroid RNA Motif by Isostericity Matrix and Mutagenesis Reveal Its Essential Role in Replication

RNA-templated RNA replication is essential for viral or viroid infection, as well as for regulation of cellular gene expression. Specific RNA motifs likely regulate various aspects of this replication. Viroids of the Pospiviroidae family, as represented by the Potato spindle tuber viroid (PSTVd), re...

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Detalhes bibliográficos
Main Authors: Zhong, Xuehua, Leontis, Neocles, Qian, Shuiming, Itaya, Asuka, Qi, Yijun, Boris-Lawrie, Kathleen, Ding, Biao
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1563885/
https://ncbi.nlm.nih.gov/pubmed/16912306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00837-06
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