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Potential Role for p53 in the Permissive Life Cycle of Human Cytomegalovirus

Infection of primary fibroblasts with human cytomegalovirus (HCMV) causes a rapid stabilization of the cellular protein p53. p53 is a major effector of the cellular damage response, and activation of this transcription factor can lead either to cell cycle arrest or to apoptosis. Viruses employ many...

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Hlavní autoři: Casavant, N. C., Luo, M. H., Rosenke, K., Winegardner, T., Zurawska, A., Fortunato, E. A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1563868/
https://ncbi.nlm.nih.gov/pubmed/16912290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00505-06
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