Integration Site Choice of a Feline Immunodeficiency Virus Vector

We mapped 226 unique integration sites in human hepatoma cells following gene transfer with a feline immunodeficiency virus (FIV)-based lentivirus vector. FIV integrated across the entire length of the transcriptional units. Microarray data indicated that FIV integration favored actively transcribed...

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Autori principali: Kang, Yubin, Moressi, Christopher J., Scheetz, Todd E., Xie, Litao, Tran, Diane Thi, Casavant, Thomas L., Ak, Prashanth, Benham, Craig J., Davidson, Beverly L., McCray, Paul B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2006
Soggetti:
Genome Replication and Regulation of Viral Gene Expression
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1563849/
https://ncbi.nlm.nih.gov/pubmed/16912328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00719-06
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