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Rational Design of Genetically Stable, Live-Attenuated Poliovirus Vaccines of All Three Serotypes: Relevance to Poliomyelitis Eradication

The global eradication of poliomyelitis caused by wild-type virus is likely to be completed within the next few years, despite immense logistic and political difficulties, and may ultimately be followed by the cessation of vaccination. However, the existing live-attenuated vaccines have the potentia...

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Detalhes bibliográficos
Main Authors: Macadam, Andrew J., Ferguson, Geraldine, Stone, David M., Meredith, Janet, Knowlson, Sarah, Auda, Ghazi, Almond, Jeffrey W., Minor, Philip D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1563845/
https://ncbi.nlm.nih.gov/pubmed/16912313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00370-06
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