Rhinovirus Replication in Human Macrophages Induces NF-κB-Dependent Tumor Necrosis Factor Alpha Production

Rhinoviruses (RV) are the major cause of acute exacerbations of asthma and chronic obstructive pulmonary disease (COPD). Rhinoviruses have been shown to activate macrophages, but rhinovirus replication in macrophages has not been reported. Tumor necrosis factor alpha (TNF-α) is implicated in the pat...

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Bibliographic Details
Main Authors: Laza-Stanca, Vasile, Stanciu, Luminita A., Message, Simon D., Edwards, Michael R., Gern, James E., Johnston, Sebastian L.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2006
Subjects:
Cellular Response to Infection
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1563804/
https://ncbi.nlm.nih.gov/pubmed/16873280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00162-06
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