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Independent Contributions of Polyomavirus Middle T and Small T to the Regulation of Early and Late Gene Expression and DNA Replication

We previously showed that murine polyomavirus mutants that lack both middle T (MT) and small T (ST) functions have a severe pleiotropic defect in early and late viral gene expression as well as genome amplification. The respective contribution of MT and ST to this phenotype was unclear. This work se...

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Autors principals: Chen, Li, Wang, Xiaoyu, Fluck, Michele M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1563708/
https://ncbi.nlm.nih.gov/pubmed/16840310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00679-06
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