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Identification of RNase 8 as a Novel Human Antimicrobial Protein

The antimicrobial activity of the human RNase A superfamily member RNase 8 was evaluated. Recombinant RNase 8 exhibited broad-spectrum microbicidal activity against potential pathogenic microorganisms (including multidrug-resistant strains) at micro- to nanomolar concentrations. Thus, RNase 8 was id...

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Detalhes bibliográficos
Main Authors: Rudolph, Bente, Podschun, Rainer, Sahly, Hany, Schubert, Sabine, Schröder, Jens M., Harder, Jürgen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1563533/
https://ncbi.nlm.nih.gov/pubmed/16940129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00246-06
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