Efficacy of Cethromycin, a New Ketolide, against Streptococcus pneumoniae Susceptible or Resistant to Erythromycin in a Murine Pneumonia Model

Cethromycin is a ketolide with in vitro activity against macrolide-sensitive and -resistant strains of Streptococcus pneumoniae. We compared its in vivo efficacy to erythromycin in a mouse model of acute pneumonia induced by two virulent clinical strains: a serotype 3 susceptible strain (P-4241) (MI...

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Hlavní autoři: Azoulay-Dupuis, E., Mohler, J., Bédos, J. P., Barau, C., Fantin, B.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2006
Témata:
Experimental Therapeutics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1563529/
https://ncbi.nlm.nih.gov/pubmed/16940099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00920-05
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