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Stochastic mRNA Synthesis in Mammalian Cells

Individual cells in genetically homogeneous populations have been found to express different numbers of molecules of specific proteins. We investigated the origins of these variations in mammalian cells by counting individual molecules of mRNA produced from a reporter gene that was stably integrated...

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Détails bibliographiques
Auteurs principaux: Raj, Arjun, Peskin, Charles S, Tranchina, Daniel, Vargas, Diana Y, Tyagi, Sanjay
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2006
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1563489/
https://ncbi.nlm.nih.gov/pubmed/17048983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0040309
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