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Adeno-associated viruses undergo substantial evolution in primates during natural infections

Adeno-associated viruses (AAVs) are single-stranded DNA viruses that are endemic in human populations without known clinical sequelae and are being evaluated as vectors for human gene therapy. To better understand the biology of this virus, we examined a number of nonhuman primate species for the pr...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Gao, Guangping, Alvira, Mauricio R., Somanathan, Suryanarayan, Lu, You, Vandenberghe, Luk H., Rux, John J., Calcedo, Roberto, Sanmiguel, Julio, Abbas, Zahra, Wilson, James M.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2003
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC156329/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12716974/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0937739100
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