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Mesenchymal progenitor self-renewal deficiency leads to age-dependent osteoporosis in Sca-1/Ly-6A null mice

The cellular and molecular mechanisms that underlie age-dependent osteoporosis, the most common disease in the Western Hemisphere, are poorly understood in part due to the lack of appropriate animal models in which to study disease progression. Here, we present a model that shows many similarities t...

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Bibliografiske detaljer
Main Authors: Bonyadi, Mortaza, Waldman, Stephen D., Liu, Danmei, Aubin, Jane E., Grynpas, Marc D., Stanford, William L.
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC156288/
https://ncbi.nlm.nih.gov/pubmed/12732718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1036475100
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