Mesenchymal progenitor self-renewal deficiency leads to age-dependent osteoporosis in Sca-1/Ly-6A null mice

The cellular and molecular mechanisms that underlie age-dependent osteoporosis, the most common disease in the Western Hemisphere, are poorly understood in part due to the lack of appropriate animal models in which to study disease progression. Here, we present a model that shows many similarities t...

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Bibliographic Details
Main Authors: Bonyadi, Mortaza, Waldman, Stephen D., Liu, Danmei, Aubin, Jane E., Grynpas, Marc D., Stanford, William L.
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 2003
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC156288/
https://ncbi.nlm.nih.gov/pubmed/12732718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1036475100
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