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Vancomycin analogues active against vanA-resistant strains inhibit bacterial transglycosylase without binding substrate
Bacterial transglycosylases are enzymes that couple the disaccharide subunits of peptidoglycan to form long carbohydrate chains. These enzymes are the target of the pentasaccharide antibiotic moenomycin as well as the proposed target of certain glycopeptides that overcome vancomycin resistance. Beca...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The National Academy of Sciences
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC156257/ https://ncbi.nlm.nih.gov/pubmed/12714684 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0931492100 |
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