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Effect of the anorectic fatty acid synthase inhibitor C75 on neuronal activity in the hypothalamus and brainstem
Intraperitoneal (i.p.) injection of C75, a fatty acid synthase inhibitor, causes a rapid (≤2-h) and persistent (to at least 24-h) ≈95% decrease in food intake. The persistent effect seems to be due to inhibition of the fasting-induced up-regulation of expression of hypothalamic orexigenic neuropepti...
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| Main Authors: | , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
The National Academy of Sciences
2003
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC156252/ https://ncbi.nlm.nih.gov/pubmed/12724522 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1031698100 |
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