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Similarity and Difference in the Unfolding of Thermophilic and Mesophilic Cold Shock Proteins Studied by Molecular Dynamics Simulations

Molecular dynamics simulations were performed to unfold a homologous pair of thermophilic and mesophilic cold shock proteins at high temperatures. The two proteins differ in just 11 of 66 residues and have very similar structures with a closed five-stranded antiparallel β-barrel. A long flexible loo...

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Autori principali: Huang, Xiaoqin, Zhou, Huan-Xiang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Biophysical Society 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1562390/
https://ncbi.nlm.nih.gov/pubmed/16844745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.082891
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